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Phenome-wide association study using research participants’ self-reported data provides insight into the Th17 and IL-17 pathway
A phenome-wide association study of variants in genes in the Th17 and IL-17 pathway was performed using self-reported phenotypes and genetic data from 521,000 research participants of 23andMe. Results replicated known associations with similar effect sizes for autoimmune traits illustrating self-rep...
Autores principales: | Ehm, Margaret G., Aponte, Jennifer L., Chiano, Mathias N., Yerges-Armstrong, Laura M., Johnson, Toby, Barker, Jonathan N., Cook, Suzanne F., Gupta, Akanksha, Hinds, David A., Li, Li, Nelson, Matthew R., Simpson, Michael A., Tian, Chao, McCarthy, Linda C., Rajpal, Deepak K., Waterworth, Dawn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665418/ https://www.ncbi.nlm.nih.gov/pubmed/29091937 http://dx.doi.org/10.1371/journal.pone.0186405 |
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