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Rodent models in Down syndrome research: impact and future opportunities

Down syndrome is caused by trisomy of chromosome 21. To date, a multiplicity of mouse models with Down-syndrome-related features has been developed to understand this complex human chromosomal disorder. These mouse models have been important for determining genotype-phenotype relationships and ident...

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Detalles Bibliográficos
Autores principales:	Herault, Yann, Delabar, Jean M., Fisher, Elizabeth M. C., Tybulewicz, Victor L. J., Yu, Eugene, Brault, Veronique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665454/ https://www.ncbi.nlm.nih.gov/pubmed/28993310 http://dx.doi.org/10.1242/dmm.029728

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