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Influence of a GSK3β phosphorylation site within the proximal C-terminus of Neurofilament-H on neurofilament dynamics

Phosphorylation of the C-terminal tail of the heavy neurofilament subunit (NF-H) impacts neurofilament (NF) axonal transport and residence within axons by fostering NF-NF associations that compete with transport. We tested the role of phosphorylation of a GSK-3β consensus site (S493) located in the...

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Detalles Bibliográficos
Autores principales: Vohnoutka, Rishel Brenna, Boumil, Edward F., Liu, Yuguan, Uchida, Atsuko, Pant, Harish C., Shea, Thomas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665472/
https://www.ncbi.nlm.nih.gov/pubmed/28882840
http://dx.doi.org/10.1242/bio.028522