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Influence of a GSK3β phosphorylation site within the proximal C-terminus of Neurofilament-H on neurofilament dynamics
Phosphorylation of the C-terminal tail of the heavy neurofilament subunit (NF-H) impacts neurofilament (NF) axonal transport and residence within axons by fostering NF-NF associations that compete with transport. We tested the role of phosphorylation of a GSK-3β consensus site (S493) located in the...
Autores principales: | Vohnoutka, Rishel Brenna, Boumil, Edward F., Liu, Yuguan, Uchida, Atsuko, Pant, Harish C., Shea, Thomas B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665472/ https://www.ncbi.nlm.nih.gov/pubmed/28882840 http://dx.doi.org/10.1242/bio.028522 |
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