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Porcine brain extract promotes osteogenic differentiation of bone marrow derived mesenchymal stem cells and bone consolidation in a rat distraction osteogenesis model
Distraction osteogenesis (DO) is the gold standard to treat large bone defects, but long consolidation period is a major limitation. Innovative efforts to promote osteogenesis are needed. Porcine brain extract (PBE) was reported to enhance the proliferation and differentiation of multiple primary ce...
Autores principales: | Xu, Jia, Sun, Yuxin, Wu, Tianyi, Wang, Bin, Liu, Yang, Zhang, Jinfang, Lee, Wayne Yukwai, Kang, Qinglin, Chai, Yimin, Li, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665543/ https://www.ncbi.nlm.nih.gov/pubmed/29091962 http://dx.doi.org/10.1371/journal.pone.0187362 |
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