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Dual roles of parathyroid hormone related protein in TGF-β1 signaling and fibronectin up-regulation in mesangial cells
Little is known about the cross-talk between parathyroid hormone (PTH) related protein (PTHrP) and TGF-β1 in mesangial cells (MCs). Our results showed that PTHrP treatment (≤3 h) induced internalization of PTH1R (PTH/PTHrP receptor)–TβRII (TGF-β type 2 receptor) complex and suppressed TGF-β1-mediate...
Autores principales: | Wu, Su-Zhen, Yang, Si-Jun, Chen, Hong-Min, Peng, Fang-Fang, Yu, Hong, Krepinsky, Joan C., Zhang, Bai-Fang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665616/ https://www.ncbi.nlm.nih.gov/pubmed/28954822 http://dx.doi.org/10.1042/BSR20171061 |
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