The ESRP1-GPR137 axis contributes to intestinal pathogenesis

Aberrant alternative pre-mRNA splicing (AS) events have been associated with several disorders. However, it is unclear whether deregulated AS directly contributes to disease. Here, we reveal a critical role of the AS regulator epithelial splicing regulator protein 1 (ESRP1) for intestinal homeostasi...

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Detalles Bibliográficos
Autores principales: Mager, Lukas Franz, Koelzer, Viktor Hendrik, Stuber, Regula, Thoo, Lester, Keller, Irene, Koeck, Ivonne, Langenegger, Maya, Simillion, Cedric, Pfister, Simona P, Faderl, Martin, Genitsch, Vera, Tcymbarevich, Irina, Juillerat, Pascal, Li, Xiaohong, Xia, Yu, Karamitopoulou, Eva, Lyck, Ruth, Zlobec, Inti, Hapfelmeier, Siegfried, Bruggmann, Rémy, McCoy, Kathy D, Macpherson, Andrew J, Müller, Christoph, Beutler, Bruce, Krebs, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665647/
https://www.ncbi.nlm.nih.gov/pubmed/28975893
http://dx.doi.org/10.7554/eLife.28366

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