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Amelioration of diet-induced steatohepatitis in mice following combined therapy with ASO-Fsp27 and fenofibrate

Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease. NAFLD progresses from benign steatosis to steatohepatitis (NASH) to cirrhosis and is linked to hepatocellular carcinoma. No targeted treatment is currently approved for NAFLD/NASH. We previously showed that fat-s...

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Detalles Bibliográficos
Autores principales: Rajamoorthi, Ananthi, Arias, Noemí, Basta, Jeannine, Lee, Richard G., Baldán, Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665668/
https://www.ncbi.nlm.nih.gov/pubmed/28874443
http://dx.doi.org/10.1194/jlr.M077941