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Dynamic regulation of EZH2 from HPSc to hepatocyte-like cell fate

Currently, drug metabolization and toxicity studies rely on the use of primary human hepatocytes and hepatoma cell lines, which both have conceivable limitations. Human pluripotent stem cell (hPSC)—derived hepatocyte-like cells (HLCs) are an alternative and valuable source of hepatocytes that can ov...

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Detalles Bibliográficos
Autores principales:	Pistoni, Mariaelena, Helsen, Nicky, Vanhove, Jolien, Boon, Ruben, Xu, Zhuofei, Ordovas, Laura, Verfaillie, Catherine M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665677/ https://www.ncbi.nlm.nih.gov/pubmed/29091973 http://dx.doi.org/10.1371/journal.pone.0186884

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