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Sporadic Meningioangiomatosis: A Series of Three Pediatric Cases

Meningioangiomatosis (MA) is a rare benign, hamartomatous lesion within the leptomeninges and cerebral cortex. Three percent of intractable epileptic patients with tumor develop MA. It may be accompanied with neurofibromatosis type II, or it may occur sporadically. Three patients, age range of 2-16...

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Autores principales: Anand, Raja, Garling, Richard J, Poulik, Janet, Sabolich, Marko, Goodrich, Dylan J, Sood, Sandeep, Harris, Carolyn A, Haridas, Abilash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665690/
https://www.ncbi.nlm.nih.gov/pubmed/29119071
http://dx.doi.org/10.7759/cureus.1640
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author Anand, Raja
Garling, Richard J
Poulik, Janet
Sabolich, Marko
Goodrich, Dylan J
Sood, Sandeep
Harris, Carolyn A
Haridas, Abilash
author_facet Anand, Raja
Garling, Richard J
Poulik, Janet
Sabolich, Marko
Goodrich, Dylan J
Sood, Sandeep
Harris, Carolyn A
Haridas, Abilash
author_sort Anand, Raja
collection PubMed
description Meningioangiomatosis (MA) is a rare benign, hamartomatous lesion within the leptomeninges and cerebral cortex. Three percent of intractable epileptic patients with tumor develop MA. It may be accompanied with neurofibromatosis type II, or it may occur sporadically. Three patients, age range of 2-16 years old, presented with episodes of seizure. The patients demonstrated no family history or stigmata of neurofibromatosis type II. Electroencephalogram (EEG) was unremarkable for epileptiform activity. Magnetic resonance imaging (MRI) revealed enhancing lesions within the frontal gyrus, the anterior cingulate gyrus, and the parietal lobe. Incomplete resection led to recurrence in one patient, and later, intraoperative ultrasound was used to achieve total resection in another patient. Each patient was seizure free on follow-up, and managed with anti-epileptic medication. Resection is the only curative treatment in 85% of MA cases. Complete resection is necessary for symptomatic treatment in cases of MA, as recurrence has been documented in this lesion. Intraoperative ultrasound is an effective imaging modality to ensure gross total resection of MA.
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spelling pubmed-56656902017-11-08 Sporadic Meningioangiomatosis: A Series of Three Pediatric Cases Anand, Raja Garling, Richard J Poulik, Janet Sabolich, Marko Goodrich, Dylan J Sood, Sandeep Harris, Carolyn A Haridas, Abilash Cureus Neurosurgery Meningioangiomatosis (MA) is a rare benign, hamartomatous lesion within the leptomeninges and cerebral cortex. Three percent of intractable epileptic patients with tumor develop MA. It may be accompanied with neurofibromatosis type II, or it may occur sporadically. Three patients, age range of 2-16 years old, presented with episodes of seizure. The patients demonstrated no family history or stigmata of neurofibromatosis type II. Electroencephalogram (EEG) was unremarkable for epileptiform activity. Magnetic resonance imaging (MRI) revealed enhancing lesions within the frontal gyrus, the anterior cingulate gyrus, and the parietal lobe. Incomplete resection led to recurrence in one patient, and later, intraoperative ultrasound was used to achieve total resection in another patient. Each patient was seizure free on follow-up, and managed with anti-epileptic medication. Resection is the only curative treatment in 85% of MA cases. Complete resection is necessary for symptomatic treatment in cases of MA, as recurrence has been documented in this lesion. Intraoperative ultrasound is an effective imaging modality to ensure gross total resection of MA. Cureus 2017-09-01 /pmc/articles/PMC5665690/ /pubmed/29119071 http://dx.doi.org/10.7759/cureus.1640 Text en Copyright © 2017, Anand et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurosurgery
Anand, Raja
Garling, Richard J
Poulik, Janet
Sabolich, Marko
Goodrich, Dylan J
Sood, Sandeep
Harris, Carolyn A
Haridas, Abilash
Sporadic Meningioangiomatosis: A Series of Three Pediatric Cases
title Sporadic Meningioangiomatosis: A Series of Three Pediatric Cases
title_full Sporadic Meningioangiomatosis: A Series of Three Pediatric Cases
title_fullStr Sporadic Meningioangiomatosis: A Series of Three Pediatric Cases
title_full_unstemmed Sporadic Meningioangiomatosis: A Series of Three Pediatric Cases
title_short Sporadic Meningioangiomatosis: A Series of Three Pediatric Cases
title_sort sporadic meningioangiomatosis: a series of three pediatric cases
topic Neurosurgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665690/
https://www.ncbi.nlm.nih.gov/pubmed/29119071
http://dx.doi.org/10.7759/cureus.1640
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