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CENP‐R acts bilaterally as a tumor suppressor and as an oncogene in the two‐stage skin carcinogenesis model

CENP‐R is a component of the CENP‐O complex, including CENP‐O, CENP‐P, CENP‐Q, CENP‐R, and CENP‐U and is constitutively localized to kinetochores throughout the cell cycle in vertebrates. CENP‐R‐deficient chicken DT40 cells are viable and show a very minor effect on mitosis. To investigate the funct...

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Detalles Bibliográficos
Autores principales: Okumura, Kazuhiro, Kagawa, Naoko, Saito, Megumi, Yoshizawa, Yasuhiro, Munakata, Haruka, Isogai, Eriko, Fukagawa, Tatsuo, Wakabayashi, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665765/
https://www.ncbi.nlm.nih.gov/pubmed/28795467
http://dx.doi.org/10.1111/cas.13348

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