miR-16 and miR-103 impact 5-HT(4) receptor signalling and correlate with symptom profile in irritable bowel syndrome

Irritable bowel syndrome (IBS) is a gut-brain disorder involving alterations in intestinal sensitivity and motility. Serotonin 5-HT(4) receptors are promising candidates in IBS pathophysiology since they regulate gut motor function and stool consistency, and targeted 5-HT(4)R selective drug interven...

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Autores principales: Wohlfarth, Carolin, Schmitteckert, Stefanie, Härtle, Janina D., Houghton, Lesley A., Dweep, Harsh, Fortea, Marina, Assadi, Ghazaleh, Braun, Alexander, Mederer, Tanja, Pöhner, Sarina, Becker, Philip P., Fischer, Christine, Granzow, Martin, Mönnikes, Hubert, Mayer, Emeran A., Sayuk, Gregory, Boeckxstaens, Guy, Wouters, Mira M., Simrén, Magnus, Lindberg, Greger, Ohlsson, Bodil, Schmidt, Peter Thelin, Dlugosz, Aldona, Agreus, Lars, Andreasson, Anna, D’Amato, Mauro, Burwinkel, Barbara, Bermejo, Justo Lorenzo, Röth, Ralph, Lasitschka, Felix, Vicario, Maria, Metzger, Marco, Santos, Javier, Rappold, Gudrun A., Martinez, Cristina, Niesler, Beate
格式: Online 文件 Texto
语言:English
出版: Nature Publishing Group UK 2017
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Article
在线阅读:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665867/
https://www.ncbi.nlm.nih.gov/pubmed/29089619
http://dx.doi.org/10.1038/s41598-017-13982-0

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665867/
https://www.ncbi.nlm.nih.gov/pubmed/29089619
http://dx.doi.org/10.1038/s41598-017-13982-0

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