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Genome-wide profiling of nardilysin target genes reveals its role in epigenetic regulation and cell cycle progression

Post-translational histone modifications, such as acetylation and methylation, are prerequisites for transcriptional regulation. The metalloendopeptidase nardilysin (Nrdc) is a H3K4me2-binding protein that controls thermoregulation and β-cell functions through its transcriptional coregulator functio...

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Detalles Bibliográficos
Autores principales: Morita, Yusuke, Ohno, Mikiko, Nishi, Kiyoto, Hiraoka, Yoshinori, Saijo, Sayaka, Matsuda, Shintaro, Kita, Toru, Kimura, Takeshi, Nishi, Eiichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665917/
https://www.ncbi.nlm.nih.gov/pubmed/29093577
http://dx.doi.org/10.1038/s41598-017-14942-4