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Genome-wide profiling of nardilysin target genes reveals its role in epigenetic regulation and cell cycle progression
Post-translational histone modifications, such as acetylation and methylation, are prerequisites for transcriptional regulation. The metalloendopeptidase nardilysin (Nrdc) is a H3K4me2-binding protein that controls thermoregulation and β-cell functions through its transcriptional coregulator functio...
Autores principales: | Morita, Yusuke, Ohno, Mikiko, Nishi, Kiyoto, Hiraoka, Yoshinori, Saijo, Sayaka, Matsuda, Shintaro, Kita, Toru, Kimura, Takeshi, Nishi, Eiichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665917/ https://www.ncbi.nlm.nih.gov/pubmed/29093577 http://dx.doi.org/10.1038/s41598-017-14942-4 |
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