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High-concentration hydrogen protects mouse heart against ischemia/reperfusion injury through activation of thePI3K/Akt1 pathway

The study investigated the role of Akt1 through the cardioprotection of high-concentration hydrogen (HCH). C57BL/6 mice were randomly divided into the following groups: sham, I/R, I/R + HCH, I/R + HCH + LY294002 (PI3K inhibitor), I/R + HCH + wortmannin (PI3K inhibitor), I/R + LY294002, and I/R + wor...

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Detalles Bibliográficos
Autores principales: Chen, Ouyang, Cao, Zhiyong, Li, He, Ye, Zhouheng, Zhang, Rongjia, Zhang, Ning, Huang, Junlong, Zhang, Ting, Wang, Liping, Han, Ling, Liu, Wenwu, Sun, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5665927/
https://www.ncbi.nlm.nih.gov/pubmed/29093541
http://dx.doi.org/10.1038/s41598-017-14072-x

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