Cargando…
Combating virulence of Gram-negative bacilli by OmpA inhibition
Preventing the adhesion of pathogens to host cells provides an innovative approach to tackling multidrug-resistant bacteria. In this regard, the identification of outer membrane protein A (OmpA) as a key bacterial virulence factor has been a major breakthrough. The use of virtual screening helped us...
Autores principales: | Vila-Farrés, Xavier, Parra-Millán, Raquel, Sánchez-Encinales, Viviana, Varese, Monica, Ayerbe-Algaba, Rafael, Bayó, Nuria, Guardiola, Salvador, Pachón-Ibáñez, María Eugenia, Kotev, Martin, García, Jesús, Teixidó, Meritxell, Vila, Jordi, Pachón, Jerónimo, Giralt, Ernest, Smani, Younes |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666006/ https://www.ncbi.nlm.nih.gov/pubmed/29089624 http://dx.doi.org/10.1038/s41598-017-14972-y |
Ejemplares similares
-
AOA-2 Derivatives as Outer Membrane Protein A Inhibitors for Treatment of Gram-Negative Bacilli Infections
por: Ayerbe-Algaba, Rafael, et al.
Publicado: (2021) -
Repurposing of the Tamoxifen Metabolites to Combat Infections by Multidrug-Resistant Gram-Negative Bacilli
por: Miró-Canturri, Andrea, et al.
Publicado: (2021) -
Potential Tamoxifen Repurposing to Combat Infections by Multidrug-Resistant Gram-Negative Bacilli
por: Miró-Canturri, Andrea, et al.
Publicado: (2021) -
Synergistic Activity of Niclosamide in Combination With Colistin Against Colistin-Susceptible and Colistin-Resistant Acinetobacter baumannii and Klebsiella pneumoniae
por: Ayerbe-Algaba, Rafael, et al.
Publicado: (2018) -
Intracellular Trafficking and Persistence of Acinetobacter baumannii Requires Transcription Factor EB
por: Parra-Millán, Raquel, et al.
Publicado: (2018)