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Direct estimation of de novo mutation rates in a chimpanzee parent-offspring trio by ultra-deep whole genome sequencing

Mutations generate genetic variation and are a major driving force of evolution. Therefore, examining mutation rates and modes are essential for understanding the genetic basis of the physiology and evolution of organisms. Here, we aim to identify germline de novo mutations through the whole-genome...

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Detalles Bibliográficos
Autores principales: Tatsumoto, Shoji, Go, Yasuhiro, Fukuta, Kentaro, Noguchi, Hideki, Hayakawa, Takashi, Tomonaga, Masaki, Hirai, Hirohisa, Matsuzawa, Tetsuro, Agata, Kiyokazu, Fujiyama, Asao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666008/
https://www.ncbi.nlm.nih.gov/pubmed/29093469
http://dx.doi.org/10.1038/s41598-017-13919-7