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Mycobacterial genomic DNA from used Xpert MTB/RIF cartridges can be utilised for accurate second-line genotypic drug susceptibility testing and spoligotyping
Xpert MTB/RIF (Xpert) is a widely-used test for tuberculosis (TB) and rifampicin-resistance. Second-line drug susceptibility testing (DST), which is recommended by policymakers, typically requires additional specimen collection that delays effective treatment initiation. We examined whether cartridg...
Autores principales: | Venter, Rouxjeane, Derendinger, Brigitta, de Vos, Margaretha, Pillay, Samantha, Dolby, Tanya, Simpson, John, Kitchin, Natasha, Ruiters, Ashley, van Helden, Paul D., Warren, Robin M., Theron, Grant |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666021/ https://www.ncbi.nlm.nih.gov/pubmed/29093504 http://dx.doi.org/10.1038/s41598-017-14385-x |
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