Solution structure of CXCL13 and heparan sulfate binding show that GAG binding site and cellular signalling rely on distinct domains

Chemokines promote directional cell migration through binding to G-protein-coupled receptors, and as such are involved in a large array of developmental, homeostatic and pathological processes. They also interact with heparan sulfate (HS), the functional consequences of which depend on the respectiv...

Descripción completa

Detalles Bibliográficos
Autores principales: Monneau, Yoan R., Luo, Lingjie, Sankaranarayanan, Nehru Viji, Nagarajan, Balaji, Vivès, Romain R., Baleux, Françoise, Desai, Umesh R., Arenzana-Seidedos, Fernando, Lortat-Jacob, Hugues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666081/
https://www.ncbi.nlm.nih.gov/pubmed/29070611
http://dx.doi.org/10.1098/rsob.170133

Ejemplares similares

Ejemplares similares