Photoactivatable RNAi for cancer gene therapy triggered by near-infrared-irradiated single-walled carbon nanotubes

The efficacy of RNA interference (RNAi)-based cancer gene therapy is limited by its unexpected side effects, thus necessitating a strategy to precisely trigger conditional gene knockdown. In this study, we engineered a novel photoactivatable RNAi system, named as polyetherimide-modified single-wall...

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Detalles Bibliográficos
Autores principales: Ren, Xueling, Lin, Jing, Wang, Xuefang, Liu, Xiao, Meng, Erjuan, Zhang, Rui, Sang, Yanxiao, Zhang, Zhenzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666115/
https://www.ncbi.nlm.nih.gov/pubmed/29138556
http://dx.doi.org/10.2147/IJN.S141882

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