Young Human Cholinergic Neurons Respond to Physiological Regulators and Improve Cognitive Symptoms in an Animal Model of Alzheimer’s Disease

The degeneration of cholinergic neurons of the nucleus basalis of Meynert (NBM) in the basal forebrain (BF) is associated to the cognitive decline of Alzheimer’s disease (AD) patients. To date no resolutive therapies exist. Cell-based replacement therapy is a strategy currently under consideration,...

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Detalles Bibliográficos
Autores principales: Morelli, Annamaria, Sarchielli, Erica, Guarnieri, Giulia, Coppi, Elisabetta, Pantano, Daniela, Comeglio, Paolo, Nardiello, Pamela, Pugliese, Anna M., Ballerini, Lara, Matucci, Rosanna, Ambrosini, Stefano, Castronovo, Giuseppe, Valente, Rosa, Mazzanti, Benedetta, Bucciantini, Sandra, Maggi, Mario, Casamenti, Fiorella, Gallina, Pasquale, Vannelli, Gabriella B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666298/
https://www.ncbi.nlm.nih.gov/pubmed/29163051
http://dx.doi.org/10.3389/fncel.2017.00339

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