Pathogen‐specific B‐cell receptors drive chronic lymphocytic leukemia by light‐chain‐dependent cross‐reaction with autoantigens

Several lines of evidence indirectly suggest that antigenic stimulation through the B‐cell receptor (BCR) supports chronic lymphocytic leukemia (CLL) development. In addition to self‐antigens, a number of microbial antigens have been proposed to contribute to the selection of the immunoglobulins exp...

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Detalles Bibliográficos
Autores principales: Jiménez de Oya, Nereida, De Giovanni, Marco, Fioravanti, Jessica, Übelhart, Rudolf, Di Lucia, Pietro, Fiocchi, Amleto, Iacovelli, Stefano, Efremov, Dimitar G, Caligaris‐Cappio, Federico, Jumaa, Hassan, Ghia, Paolo, Guidotti, Luca G, Iannacone, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666309/
https://www.ncbi.nlm.nih.gov/pubmed/28899929
http://dx.doi.org/10.15252/emmm.201707732

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