Genome editing for scalable production of alloantigen‐free lentiviral vectors for in vivo gene therapy

Lentiviral vectors (LV) are powerful and versatile vehicles for gene therapy. However, their complex biological composition challenges large‐scale manufacturing and raises concerns for in vivo applications, because particle components and contaminants may trigger immune responses. Here, we show that...

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Detalles Bibliográficos
Autores principales: Milani, Michela, Annoni, Andrea, Bartolaccini, Sara, Biffi, Mauro, Russo, Fabio, Di Tomaso, Tiziano, Raimondi, Andrea, Lengler, Johannes, Holmes, Michael C, Scheiflinger, Friedrich, Lombardo, Angelo, Cantore, Alessio, Naldini, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666310/
https://www.ncbi.nlm.nih.gov/pubmed/28835507
http://dx.doi.org/10.15252/emmm.201708148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666310/
https://www.ncbi.nlm.nih.gov/pubmed/28835507
http://dx.doi.org/10.15252/emmm.201708148

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