Cargando…
Disease‐modifying effects of ganglioside GM1 in Huntington's disease models
Huntington's disease (HD) is a progressive neurodegenerative disorder characterized by motor, cognitive and psychiatric problems. Previous studies indicated that levels of brain gangliosides are lower than normal in HD models and that administration of exogenous ganglioside GM1 corrects motor d...
Autores principales: | Alpaugh, Melanie, Galleguillos, Danny, Forero, Juan, Morales, Luis Carlos, Lackey, Sebastian W, Kar, Preeti, Di Pardo, Alba, Holt, Andrew, Kerr, Bradley J, Todd, Kathryn G, Baker, Glen B, Fouad, Karim, Sipione, Simonetta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666311/ https://www.ncbi.nlm.nih.gov/pubmed/28993428 http://dx.doi.org/10.15252/emmm.201707763 |
Ejemplares similares
-
Naïve Huntington’s disease microglia mount a normal response to inflammatory stimuli but display a partially impaired development of innate immune tolerance that can be counteracted by ganglioside GM1
por: Steinberg, Noam, et al.
Publicado: (2023) -
Gangliosides in the Brain: Physiology, Pathophysiology and Therapeutic Applications
por: Sipione, Simonetta, et al.
Publicado: (2020) -
Anti-inflammatory role of GM1 and other gangliosides on microglia
por: Galleguillos, Danny, et al.
Publicado: (2022) -
The cytoprotective role of GM1 ganglioside in Huntington disease cells
por: Hart, Hannah S., et al.
Publicado: (2022) -
Impaired Levels of Gangliosides in the Corpus Callosum of Huntington Disease Animal Models
por: Di Pardo, Alba, et al.
Publicado: (2016)