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Disease‐modifying effects of ganglioside GM1 in Huntington's disease models

Huntington's disease (HD) is a progressive neurodegenerative disorder characterized by motor, cognitive and psychiatric problems. Previous studies indicated that levels of brain gangliosides are lower than normal in HD models and that administration of exogenous ganglioside GM1 corrects motor d...

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Detalles Bibliográficos
Autores principales: Alpaugh, Melanie, Galleguillos, Danny, Forero, Juan, Morales, Luis Carlos, Lackey, Sebastian W, Kar, Preeti, Di Pardo, Alba, Holt, Andrew, Kerr, Bradley J, Todd, Kathryn G, Baker, Glen B, Fouad, Karim, Sipione, Simonetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666311/
https://www.ncbi.nlm.nih.gov/pubmed/28993428
http://dx.doi.org/10.15252/emmm.201707763

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