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Understanding the Mechanism of Translocation of Adenylate Cyclase Toxin across Biological Membranes

Adenylate cyclase toxin (ACT) is one of the principal virulence factors secreted by the whooping cough causative bacterium Bordetella pertussis, and it has a critical role in colonization of the respiratory tract and establishment of the disease. ACT targets phagocytes via binding to the CD11b/CD18...

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Detalles Bibliográficos
Autores principales: Ostolaza, Helena, Martín, César, González-Bullón, David, Uribe, Kepa B., Etxaniz, Asier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666342/
https://www.ncbi.nlm.nih.gov/pubmed/28934133
http://dx.doi.org/10.3390/toxins9100295