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Understanding the Mechanism of Translocation of Adenylate Cyclase Toxin across Biological Membranes
Adenylate cyclase toxin (ACT) is one of the principal virulence factors secreted by the whooping cough causative bacterium Bordetella pertussis, and it has a critical role in colonization of the respiratory tract and establishment of the disease. ACT targets phagocytes via binding to the CD11b/CD18...
Autores principales: | Ostolaza, Helena, Martín, César, González-Bullón, David, Uribe, Kepa B., Etxaniz, Asier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666342/ https://www.ncbi.nlm.nih.gov/pubmed/28934133 http://dx.doi.org/10.3390/toxins9100295 |
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