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Evaluation of Sox2 binding affinities for distinct DNA patterns using steered molecular dynamics simulation

Transcription factors (TFs) are gene expression regulators that bind to DNA in a sequence‐specific manner and determine the functional characteristics of the gene. It is worthwhile to study the unique characteristics of such specific TF‐binding pattern in DNA. Sox2 recognizes a 6‐ to 7‐base pair con...

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Detalles Bibliográficos
Autores principales:	Yesudhas, Dhanusha, Anwar, Muhammad Ayaz, Panneerselvam, Suresh, Kim, Han‐Kyul, Choi, Sangdun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666385/ https://www.ncbi.nlm.nih.gov/pubmed/29123983 http://dx.doi.org/10.1002/2211-5463.12316

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