Cargando…
Marine-Derived 2-Aminoimidazolone Alkaloids. Leucettamine B-Related Polyandrocarpamines Inhibit Mammalian and Protozoan DYRK & CLK Kinases
A large diversity of 2-aminoimidazolone alkaloids is produced by various marine invertebrates, especially by the marine Calcareous sponges Leucetta and Clathrina. The phylogeny of these sponges and the wide scope of 2-aminoimidazolone alkaloids they produce are reviewed in this article. The origin (...
Autores principales: | Loaëc, Nadège, Attanasio, Eletta, Villiers, Benoît, Durieu, Emilie, Tahtouh, Tania, Cam, Morgane, Davis, Rohan A., Alencar, Aline, Roué, Mélanie, Bourguet-Kondracki, Marie-Lise, Proksch, Peter, Limanton, Emmanuelle, Guiheneuf, Solène, Carreaux, François, Bazureau, Jean-Pierre, Klautau, Michelle, Meijer, Laurent |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666424/ https://www.ncbi.nlm.nih.gov/pubmed/29039762 http://dx.doi.org/10.3390/md15100316 |
Ejemplares similares
-
Design and Microwave Synthesis of New (5Z) 5-Arylidene-2-thioxo-1,3-thiazolinidin-4-one and (5Z) 2-Amino-5-arylidene-1,3-thiazol-4(5H)-one as New Inhibitors of Protein Kinase DYRK1A
por: Bourahla, Khadidja, et al.
Publicado: (2021) -
Correction of cognitive deficits in mouse models of Down syndrome by a pharmacological inhibitor of DYRK1A
por: Nguyen, Thu Lan, et al.
Publicado: (2018) -
Inhibition of DYRK1A proteolysis modifies its kinase specificity and rescues Alzheimer phenotype in APP/PS1 mice
por: Souchet, Benoît, et al.
Publicado: (2019) -
SGC-CLK-1: A chemical probe for the Cdc2-like kinases CLK1, CLK2, and CLK4
por: Tiek, Deanna, et al.
Publicado: (2023) -
Design and Synthesis of a Library of Lead-Like 2,4-Bisheterocyclic Substituted Thiophenes as Selective Dyrk/Clk Inhibitors
por: Schmitt, Christian, et al.
Publicado: (2014)