Recent Advances in the Isolation, Synthesis and Biological Activity of Marine Guanidine Alkaloids

Marine organisms are prolific resources of guanidine-containing natural products with intriguing structures and promising biological activities. These molecules have therefore attracted the attention of chemists and biologists for their further studies towards potential drug leads. This review focus...

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Detalles Bibliográficos
Autores principales: Liu, Jin, Li, Xu-Wen, Guo, Yue-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666430/
https://www.ncbi.nlm.nih.gov/pubmed/29064383
http://dx.doi.org/10.3390/md15100324
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author Liu, Jin
Li, Xu-Wen
Guo, Yue-Wei
author_facet Liu, Jin
Li, Xu-Wen
Guo, Yue-Wei
author_sort Liu, Jin
collection PubMed
description Marine organisms are prolific resources of guanidine-containing natural products with intriguing structures and promising biological activities. These molecules have therefore attracted the attention of chemists and biologists for their further studies towards potential drug leads. This review focused on the guanidine alkaloids derived from marine sources and discussed the recent progress on their isolation, synthesis and biological activities, covering the literature from the year 2010 to the present.
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spelling pubmed-56664302017-11-09 Recent Advances in the Isolation, Synthesis and Biological Activity of Marine Guanidine Alkaloids Liu, Jin Li, Xu-Wen Guo, Yue-Wei Mar Drugs Review Marine organisms are prolific resources of guanidine-containing natural products with intriguing structures and promising biological activities. These molecules have therefore attracted the attention of chemists and biologists for their further studies towards potential drug leads. This review focused on the guanidine alkaloids derived from marine sources and discussed the recent progress on their isolation, synthesis and biological activities, covering the literature from the year 2010 to the present. MDPI 2017-10-24 /pmc/articles/PMC5666430/ /pubmed/29064383 http://dx.doi.org/10.3390/md15100324 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Liu, Jin
Li, Xu-Wen
Guo, Yue-Wei
Recent Advances in the Isolation, Synthesis and Biological Activity of Marine Guanidine Alkaloids
title Recent Advances in the Isolation, Synthesis and Biological Activity of Marine Guanidine Alkaloids
title_full Recent Advances in the Isolation, Synthesis and Biological Activity of Marine Guanidine Alkaloids
title_fullStr Recent Advances in the Isolation, Synthesis and Biological Activity of Marine Guanidine Alkaloids
title_full_unstemmed Recent Advances in the Isolation, Synthesis and Biological Activity of Marine Guanidine Alkaloids
title_short Recent Advances in the Isolation, Synthesis and Biological Activity of Marine Guanidine Alkaloids
title_sort recent advances in the isolation, synthesis and biological activity of marine guanidine alkaloids
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666430/
https://www.ncbi.nlm.nih.gov/pubmed/29064383
http://dx.doi.org/10.3390/md15100324
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