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Effect of prophylactic non-invasive mechanical ventilation on functional capacity after heart valve replacement: a clinical trial

OBJECTIVE: During cardiac surgery, several factors contribute to the development of postoperative pulmonary complications. Non-invasive ventilation is a promising therapeutic tool for improving the functionality of this type of patient. The aim of this study is to evaluate the functional capacity an...

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Autores principales: de Araújo-Filho, Amaro Afrânio, de Cerqueira-Neto, Manoel Luiz, de Assis Pereira Cacau, Lucas, Oliveira, Géssica Uruga, Cerqueira, Telma Cristina Fontes, de Santana-Filho, Valter Joviniano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666445/
https://www.ncbi.nlm.nih.gov/pubmed/29160424
http://dx.doi.org/10.6061/clinics/2017(10)05
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author de Araújo-Filho, Amaro Afrânio
de Cerqueira-Neto, Manoel Luiz
de Assis Pereira Cacau, Lucas
Oliveira, Géssica Uruga
Cerqueira, Telma Cristina Fontes
de Santana-Filho, Valter Joviniano
author_facet de Araújo-Filho, Amaro Afrânio
de Cerqueira-Neto, Manoel Luiz
de Assis Pereira Cacau, Lucas
Oliveira, Géssica Uruga
Cerqueira, Telma Cristina Fontes
de Santana-Filho, Valter Joviniano
author_sort de Araújo-Filho, Amaro Afrânio
collection PubMed
description OBJECTIVE: During cardiac surgery, several factors contribute to the development of postoperative pulmonary complications. Non-invasive ventilation is a promising therapeutic tool for improving the functionality of this type of patient. The aim of this study is to evaluate the functional capacity and length of stay of patients in a nosocomial intensive care unit who underwent prophylactic non-invasive ventilation after heart valve replacement. METHOD: The study was a controlled clinical trial, comprising 50 individuals of both sexes who were allocated by randomization into two groups with 25 patients in each group: the control group and experimental group. After surgery, the patients were transferred to the intensive care unit and then participated in standard physical therapy, which was provided to the experimental group after 3 applications of non-invasive ventilation within the first 26 hours after extubation. For non-invasive ventilation, the positive pressure was 10 cm H(2)O, with a duration of 1 hour. The evaluation was performed on the 7(th) postoperative day/discharge and included a 6-minute walk test. The intensive care unit and hospitalization times were monitored in both groups. Brazilian Registry of Clinical Trials (REBeC): RBR number 8bxdd3. RESULTS: Analysis of the 6-minute walk test showed that the control group walked an average distance of 264.34±76 meters and the experimental group walked an average distance of 334.07±71 meters (p=0.002). The intensive care unit and hospitalization times did not differ between the groups. CONCLUSION: Non-invasive ventilation as a therapeutic resource was effective toward improving functionality; however, non-invasive ventilation did not influence the intensive care unit or hospitalization times of the studied cardiac patients.
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spelling pubmed-56664452017-11-07 Effect of prophylactic non-invasive mechanical ventilation on functional capacity after heart valve replacement: a clinical trial de Araújo-Filho, Amaro Afrânio de Cerqueira-Neto, Manoel Luiz de Assis Pereira Cacau, Lucas Oliveira, Géssica Uruga Cerqueira, Telma Cristina Fontes de Santana-Filho, Valter Joviniano Clinics (Sao Paulo) Clinical Science OBJECTIVE: During cardiac surgery, several factors contribute to the development of postoperative pulmonary complications. Non-invasive ventilation is a promising therapeutic tool for improving the functionality of this type of patient. The aim of this study is to evaluate the functional capacity and length of stay of patients in a nosocomial intensive care unit who underwent prophylactic non-invasive ventilation after heart valve replacement. METHOD: The study was a controlled clinical trial, comprising 50 individuals of both sexes who were allocated by randomization into two groups with 25 patients in each group: the control group and experimental group. After surgery, the patients were transferred to the intensive care unit and then participated in standard physical therapy, which was provided to the experimental group after 3 applications of non-invasive ventilation within the first 26 hours after extubation. For non-invasive ventilation, the positive pressure was 10 cm H(2)O, with a duration of 1 hour. The evaluation was performed on the 7(th) postoperative day/discharge and included a 6-minute walk test. The intensive care unit and hospitalization times were monitored in both groups. Brazilian Registry of Clinical Trials (REBeC): RBR number 8bxdd3. RESULTS: Analysis of the 6-minute walk test showed that the control group walked an average distance of 264.34±76 meters and the experimental group walked an average distance of 334.07±71 meters (p=0.002). The intensive care unit and hospitalization times did not differ between the groups. CONCLUSION: Non-invasive ventilation as a therapeutic resource was effective toward improving functionality; however, non-invasive ventilation did not influence the intensive care unit or hospitalization times of the studied cardiac patients. Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2017-10 2017-10 /pmc/articles/PMC5666445/ /pubmed/29160424 http://dx.doi.org/10.6061/clinics/2017(10)05 Text en Copyright © 2017 CLINICS http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.
spellingShingle Clinical Science
de Araújo-Filho, Amaro Afrânio
de Cerqueira-Neto, Manoel Luiz
de Assis Pereira Cacau, Lucas
Oliveira, Géssica Uruga
Cerqueira, Telma Cristina Fontes
de Santana-Filho, Valter Joviniano
Effect of prophylactic non-invasive mechanical ventilation on functional capacity after heart valve replacement: a clinical trial
title Effect of prophylactic non-invasive mechanical ventilation on functional capacity after heart valve replacement: a clinical trial
title_full Effect of prophylactic non-invasive mechanical ventilation on functional capacity after heart valve replacement: a clinical trial
title_fullStr Effect of prophylactic non-invasive mechanical ventilation on functional capacity after heart valve replacement: a clinical trial
title_full_unstemmed Effect of prophylactic non-invasive mechanical ventilation on functional capacity after heart valve replacement: a clinical trial
title_short Effect of prophylactic non-invasive mechanical ventilation on functional capacity after heart valve replacement: a clinical trial
title_sort effect of prophylactic non-invasive mechanical ventilation on functional capacity after heart valve replacement: a clinical trial
topic Clinical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666445/
https://www.ncbi.nlm.nih.gov/pubmed/29160424
http://dx.doi.org/10.6061/clinics/2017(10)05
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