Membrane-Fusogen Distance Is Critical for Efficient Coiled-Coil-Peptide-Mediated Liposome Fusion

[Image: see text] We have developed a model system for membrane fusion that utilizes lipidated derivatives of a heterodimeric coiled-coil pair dubbed E(3) (EIAALEK)(3) and K(3) (KIAALKE)(3). In this system, peptides are conjugated to a lipid anchor via a poly(ethylene glycol) (PEG) spacer, and this...

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Detalles Bibliográficos
Autores principales: Daudey, Geert A., Zope, Harshal R., Voskuhl, Jens, Kros, Alexander, Boyle, Aimee L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666511/
https://www.ncbi.nlm.nih.gov/pubmed/28980816
http://dx.doi.org/10.1021/acs.langmuir.7b02931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666511/
https://www.ncbi.nlm.nih.gov/pubmed/28980816
http://dx.doi.org/10.1021/acs.langmuir.7b02931

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