Clenbuterol Induces Cell Cycle Arrest in C2C12 Myoblasts by Delaying p27 Degradation through β-arrestin 2 Signaling

β(2)-Adrenoceptor (β(2)-AR) agonists promote muscle growth. The aim of this study was to elucidate some effects of the selective β(2)-adrenoceptor agonist clenbuterol (CLB) on myoblast proliferation. We found that CLB induces cell cycle arrest in C2C12 myoblasts. This effect is partly due to the enh...

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Detalles Bibliográficos
Autores principales: Chen, Min, Liu, Chuncheng, Wang, Meng, Wang, Hong, Zhang, Kuo, Zheng, Yu, Yu, Zhengquan, Li, Xiangdong, Guo, Wei, Li, Ning, Meng, Qingyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666532/
https://www.ncbi.nlm.nih.gov/pubmed/29104500
http://dx.doi.org/10.7150/ijbs.17948

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