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The inhibition of indoleamine 2, 3-dioxygenase 1 by connexin 43
Upregulation of connexin 43 (Cx43) showed potential in enhancing immune surveillance that was suppressed in the tumor microenvironment. The expression of indoleamine 2, 3-dioxygenase (IDO) is one of the crucial factors contributing to tumor immune tolerance by depletion of tryptophan and IDO-mediate...
Autores principales: | Lin, Han-Chen, Yang, Chih-Jen, Kuan, Yu-Diao, Wang, Wei-Kuang, Chang, Wen-Wei, Lee, Che-Hsin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666550/ https://www.ncbi.nlm.nih.gov/pubmed/29104473 http://dx.doi.org/10.7150/ijms.20661 |
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