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Aubergine and piRNAs promote germline stem cell self‐renewal by repressing the proto‐oncogene Cbl

PIWI proteins play essential roles in germ cells and stem cell lineages. In Drosophila, Piwi is required in somatic niche cells and germline stem cells (GSCs) to support GSC self‐renewal and differentiation. Whether and how other PIWI proteins are involved in GSC biology remains unknown. Here, we sh...

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Detalles Bibliográficos
Autores principales: Rojas‐Ríos, Patricia, Chartier, Aymeric, Pierson, Stéphanie, Simonelig, Martine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666619/
https://www.ncbi.nlm.nih.gov/pubmed/29030484
http://dx.doi.org/10.15252/embj.201797259