ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression

Direct reprogramming of fibroblasts to cardiomyocytes represents a potential means of restoring cardiac function following myocardial injury. AKT1 in the presence of four cardiogenic transcription factors, GATA4, HAND2, MEF2C, and TBX5 (AGHMT), efficiently induces the cardiac gene program in mouse e...

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Detalles Bibliográficos
Autores principales: Zhou, Huanyu, Morales, Maria Gabriela, Hashimoto, Hisayuki, Dickson, Matthew E., Song, Kunhua, Ye, Wenduo, Kim, Min S., Niederstrasser, Hanspeter, Wang, Zhaoning, Chen, Beibei, Posner, Bruce A., Bassel-Duby, Rhonda, Olson, Eric N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666675/
https://www.ncbi.nlm.nih.gov/pubmed/28982760
http://dx.doi.org/10.1101/gad.305482.117

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