Integrator orchestrates RAS/ERK1/2 signaling transcriptional programs

Activating mutations in the mitogen-activated protein kinase (MAPK) cascade, also known as the RAS–MEK–extracellular signal-related kinase (ERK1/2) pathway, are an underlying cause of >70% of human cancers. While great strides have been made toward elucidating the cytoplasmic components of MAPK s...

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Detalles Bibliográficos
Autores principales: Yue, Jingyin, Lai, Fan, Beckedorff, Felipe, Zhang, Anda, Pastori, Chiara, Shiekhattar, Ramin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666678/
https://www.ncbi.nlm.nih.gov/pubmed/28982763
http://dx.doi.org/10.1101/gad.301697.117

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