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Proteome Stability as a Key Factor of Genome Integrity

DNA damage is constantly produced by both endogenous and exogenous factors; DNA lesions then trigger the so-called DNA damaged response (DDR). This is a highly synchronized pathway that involves recognition, signaling and repair of the damage. Failure to eliminate DNA lesions is associated with geno...

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Detalles Bibliográficos
Autores principales:	Gumeni, Sentiljana, Evangelakou, Zoi, Gorgoulis, Vassilis G., Trougakos, Ioannis P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666718/ https://www.ncbi.nlm.nih.gov/pubmed/28937603 http://dx.doi.org/10.3390/ijms18102036

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