Cargando…

Challenges and Strategies for Improving the Regenerative Effects of Mesenchymal Stromal Cell-Based Therapies

Cell-based therapies have the potential to revolutionize current treatments for diseases with high prevalence and related economic and social burden. Unfortunately, clinical trials have made only modest improvements in restoring normal function to degenerating tissues. This limitation is due, at lea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baldari, Silvia, Di Rocco, Giuliana, Piccoli, Martina, Pozzobon, Michela, Muraca, Maurizio, Toietta, Gabriele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666769/ https://www.ncbi.nlm.nih.gov/pubmed/28974046 http://dx.doi.org/10.3390/ijms18102087

Ejemplares similares

Extracellular Vesicles–Encapsulated MicroRNA-125b Produced in Genetically Modified Mesenchymal Stromal Cells Inhibits Hepatocellular Carcinoma Cell Proliferation
por: Baldari, Silvia, et al.
Publicado: (2019)

Towards Therapeutic Delivery of Extracellular Vesicles: Strategies for In Vivo Tracking and Biodistribution Analysis
por: Di Rocco, Giuliana, et al.
Publicado: (2016)

Regenerative medicine approaches for the management of respiratory tract fistulas
por: Trivisonno, Angelo, et al.
Publicado: (2020)

Current Biomedical Use of Copper Chelation Therapy
por: Baldari, Silvia, et al.
Publicado: (2020)

Promotion of Survival and Engraftment of Transplanted Adipose Tissue-Derived Stromal and Vascular Cells by Overexpression of Manganese Superoxide Dismutase
por: Baldari, Silvia, et al.
Publicado: (2016)

Diverging Concepts and Novel Perspectives in Regenerative Medicine
por: Muraca, Maurizio, et al.
Publicado: (2017)

Protein disulfide isomerase as a prosurvival factor in cell therapy for muscular and vascular diseases
por: Di Rocco, Giuliana, et al.
Publicado: (2018)

Stem cells under the influence of alcohol: effects of ethanol consumption on stem/progenitor cells
por: Di Rocco, Giuliana, et al.
Publicado: (2018)

Strategies for Efficient Targeting of Tumor Collagen for Cancer Therapy
por: Baldari, Silvia, et al.
Publicado: (2022)

Reduction of Cell Proliferation by Acute C(2)H(6)O Exposure
por: Baldari, Silvia, et al.
Publicado: (2021)

Enhanced Healing of Diabetic Wounds by Topical Administration of Adipose Tissue-Derived Stromal Cells Overexpressing Stromal-Derived Factor-1: Biodistribution and Engraftment Analysis by Bioluminescent Imaging
por: Di Rocco, Giuliana, et al.
Publicado: (2010)

Effects of Copper Chelation on BRAF(V600E) Positive Colon Carcinoma Cells
por: Baldari, Silvia, et al.
Publicado: (2019)

Mesenchymal stromal cells and their secreted extracellular vesicles as therapeutic tools for COVID-19 pneumonia?()
por: Muraca, Maurizio, et al.
Publicado: (2020)

Intraoperative Strategies for Minimal Manipulation of Autologous Adipose Tissue for Cell‐ and Tissue‐Based Therapies: Concise Review
por: Trivisonno, Angelo, et al.
Publicado: (2019)

Extracellular Vesicles Secreted by Mesenchymal Stromal Cells Exert Opposite Effects to Their Cells of Origin in Murine Sodium Dextran Sulfate-Induced Colitis
por: Tolomeo, Anna Maria, et al.
Publicado: (2021)

Veterinary Regenerative Medicine for Musculoskeletal Disorders: Can Mesenchymal Stem/Stromal Cells and Their Secretome Be the New Frontier?
por: Mocchi, Michela, et al.
Publicado: (2020)

Human epicardium-derived cells fuse with high efficiency with skeletal myotubes and differentiate toward the skeletal muscle phenotype: a comparison study with stromal and endothelial cells
por: Gentile, Antonietta, et al.
Publicado: (2011)

Genetic Engineering as a Strategy to Improve the Therapeutic Efficacy of Mesenchymal Stem/Stromal Cells in Regenerative Medicine
por: Damasceno, Patricia Kauanna Fonseca, et al.
Publicado: (2020)

Strategies to improve regenerative potential of mesenchymal stem cells
por: Choudhery, Mahmood S
Publicado: (2021)

Editorial: Mesenchymal Stromal Cell Therapy for Regenerative Medicine
por: Capilla-González, Vivian, et al.
Publicado: (2022)

Human umbilical cord mesenchymal stromal cells in regenerative medicine
por: Detamore, Michael S
Publicado: (2013)

Mesenchymal stromal cells: main factor or helper in regenerative medicine?
por: Zander, Axel R, et al.
Publicado: (2011)

Regenerative Potential of Mesenchymal Stromal Cells: Age-Related Changes
por: Bruna, Flavia, et al.
Publicado: (2016)

Collagen scaffold enhances the regenerative properties of mesenchymal stromal cells
por: Rashedi, Iran, et al.
Publicado: (2017)

Mesenchymal Stromal/Stem Cells in Regenerative Medicine and Tissue Engineering
por: Fitzsimmons, Ross E. B., et al.
Publicado: (2018)

The application of resveratrol to mesenchymal stromal cell-based regenerative medicine
por: Hu, Chenxia, et al.
Publicado: (2019)

Mesenchymal stem/stromal cell-derived exosomes in regenerative medicine and cancer; overview of development, challenges, and opportunities
por: Hassanzadeh, Ali, et al.
Publicado: (2021)

Biodistribution of Intratracheal, Intranasal, and Intravenous Injections of Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles in a Mouse Model for Drug Delivery Studies
por: Tolomeo, Anna Maria, et al.
Publicado: (2023)

Strategies to improve the therapeutic effects of mesenchymal stromal cells in respiratory diseases
por: Silva, Luisa H. A., et al.
Publicado: (2018)

Apoptosis induced by a HIPK2 full-length-specific siRNA is due to off-target effects rather than prevalence of HIPK2-Δe8 isoform
por: Di Rocco, Giuliana, et al.
Publicado: (2015)

p53-Dependent PUMA to DRAM antagonistic interplay as a key molecular switch in cell-fate decision in normal/high glucose conditions
por: Garufi, Alessia, et al.
Publicado: (2017)

Mesenchymal Stromal Cell Homing: Mechanisms and Strategies for Improvement
por: Ullah, Mujib, et al.
Publicado: (2019)

Mesenchymal stromal cell‐derived extracellular vesicles for regenerative therapy and immune modulation: Progress and challenges toward clinical application
por: Allan, David, et al.
Publicado: (2019)

Renal Regenerative Potential of Extracellular Vesicles Derived from miRNA-Engineered Mesenchymal Stromal Cells
por: Tapparo, Marta, et al.
Publicado: (2019)

Molecular Profiles of Cell-to-Cell Variation in the Regenerative Potential of Mesenchymal Stromal Cells
por: O'Connor, Kim C.
Publicado: (2019)

Reparative and Regenerative Effects of Mesenchymal Stromal Cells—Promising Potential for Kidney Transplantation?
por: Pool, Merel, et al.
Publicado: (2019)

Pro-regenerative Dialogue Between Macrophages and Mesenchymal Stem/Stromal Cells in Osteoarthritis
por: Bohaud, Candice, et al.
Publicado: (2021)

Dental mesenchymal stromal/stem cells in different microenvironments— implications in regenerative therapy
por: Okić-Đorđević, Ivana, et al.
Publicado: (2021)

Mesenchymal stem/stromal cells in the pathogenesis and regenerative therapy of inflammatory bowel diseases
por: Che, Zhengping, et al.
Publicado: (2022)

Clinical utility of mesenchymal stem/stromal cells in regenerative medicine and cellular therapy
por: Maldonado, Vitali V., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_63j2chhlvtq1b82hio1mglnld9