Rebalancing β-Amyloid-Induced Decrease of ATP Level by Amorphous Nano/Micro Polyphosphate: Suppression of the Neurotoxic Effect of Amyloid β-Protein Fragment 25-35

Morbus Alzheimer neuropathology is characterized by an impaired energy homeostasis of brain tissue. We present an approach towards a potential therapy of Alzheimer disease based on the high-energy polymer inorganic polyphosphate (polyP), which physiologically occurs both in the extracellular and in...

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Detalles Bibliográficos
Autores principales: Müller, Werner E. G., Wang, Shunfeng, Ackermann, Maximilian, Neufurth, Meik, Steffen, Renate, Mecja, Egherta, Muñoz-Espí, Rafael, Feng, Qingling, Schröder, Heinz C., Wang, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666835/
https://www.ncbi.nlm.nih.gov/pubmed/29035351
http://dx.doi.org/10.3390/ijms18102154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666835/
https://www.ncbi.nlm.nih.gov/pubmed/29035351
http://dx.doi.org/10.3390/ijms18102154

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