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Isoproterenol Increases RANKL Expression in a ATF4/NFATc1-Dependent Manner in Mouse Osteoblastic Cells

Sympathetic nervous system stimulation-induced β-adrenergic signal transduction is known to induce bone loss and increase of osteoclast activity. Although isoproterenol, a nonspecific β-adrenergic receptor agonist, has been shown to increase receptor activator of NF-κB ligand (RANKL), the details of...

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Detalles Bibliográficos
Autores principales: Baek, Kyunghwa, Park, Hyun-Jung, Baek, Jeong-Hwa, Kim, Hyung-Ryong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666884/
https://www.ncbi.nlm.nih.gov/pubmed/29053621
http://dx.doi.org/10.3390/ijms18102204