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Isoproterenol Increases RANKL Expression in a ATF4/NFATc1-Dependent Manner in Mouse Osteoblastic Cells
Sympathetic nervous system stimulation-induced β-adrenergic signal transduction is known to induce bone loss and increase of osteoclast activity. Although isoproterenol, a nonspecific β-adrenergic receptor agonist, has been shown to increase receptor activator of NF-κB ligand (RANKL), the details of...
Autores principales: | Baek, Kyunghwa, Park, Hyun-Jung, Baek, Jeong-Hwa, Kim, Hyung-Ryong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666884/ https://www.ncbi.nlm.nih.gov/pubmed/29053621 http://dx.doi.org/10.3390/ijms18102204 |
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