Cargando…

Clinical trial protocol for TARDOX: a phase I study to investigate the feasibility of targeted release of lyso-thermosensitive liposomal doxorubicin (ThermoDox®) using focused ultrasound in patients with liver tumours

BACKGROUND: TARDOX is a Phase I single center study of ultrasound triggered targeted drug delivery in adult oncology patients with incurable liver tumours. This proof of concept study is designed to demonstrate the safety and feasibility of targeted drug release and enhanced delivery of doxorubicin...

Descripción completa

Detalles Bibliográficos
Autores principales: Lyon, Paul C., Griffiths, Lucy F., Lee, Jenni, Chung, Daniel, Carlisle, Robert, Wu, Feng, Middleton, Mark R., Gleeson, Fergus V., Coussios, Constantin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667032/
https://www.ncbi.nlm.nih.gov/pubmed/29118984
http://dx.doi.org/10.1186/s40349-017-0104-0