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Sequential Delivery of Cyclopeptide RA-V and Doxorubicin for Combination Therapy on Resistant Tumor and In Situ Monitoring of Cytochrome c Release
A programmed drug delivery system that can achieve sequential release of multiple therapeutics under different stimulus holds great promise to enhance the treatment efficacy and overcome multi-drug resistance (MDR) in tumor. Herein, multi-organelle-targeted and pH/ cytochrome c (Cyt c) dual-responsi...
Autores principales: | Chen, Huachao, Wang, Yurong, Yao, Yongrong, Qiao, Shenglin, Wang, Hao, Tan, Ninghua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667348/ https://www.ncbi.nlm.nih.gov/pubmed/29109776 http://dx.doi.org/10.7150/thno.20892 |
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