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Decrease in Lymphoid Specific Helicase and 5-hydroxymethylcytosine Is Associated with Metastasis and Genome Instability

DNA methylation is an important epigenetic modification as a hallmark in cancer. Conversion of 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC) by ten-eleven translocation (TET) family enzymes plays an important biological role in embryonic stem cells, development, aging and disease. Lymph...

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Detalles Bibliográficos
Autores principales:	Jia, Jiantao, Shi, Ying, Chen, Ling, Lai, Weiwei, Yan, Bin, Jiang, Yiqun, Xiao, Desheng, Xi, Sichuan, Cao, Ya, Liu, Shuang, Cheng, Yan, Tao, Yongguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667415/ https://www.ncbi.nlm.nih.gov/pubmed/29109788 http://dx.doi.org/10.7150/thno.21389

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