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Prevalence of adhesions and associated postoperative complications after cesarean section in Ghana: a prospective cohort study

BACKGROUND: The global increase in Cesarean section rate is associated with short- and long-term complications, including adhesions with potential serious maternal and fetal consequences. This study investigated the prevalence of adhesions and association between adhesions and postoperative complica...

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Autores principales: Nuamah, Mercy A., Browne, Joyce L., Öry, Alexander V., Damale, Nelson, Klipstein-Grobusch, Kerstin, Rijken, Marcus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667441/
https://www.ncbi.nlm.nih.gov/pubmed/29096649
http://dx.doi.org/10.1186/s12978-017-0388-0
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author Nuamah, Mercy A.
Browne, Joyce L.
Öry, Alexander V.
Damale, Nelson
Klipstein-Grobusch, Kerstin
Rijken, Marcus J.
author_facet Nuamah, Mercy A.
Browne, Joyce L.
Öry, Alexander V.
Damale, Nelson
Klipstein-Grobusch, Kerstin
Rijken, Marcus J.
author_sort Nuamah, Mercy A.
collection PubMed
description BACKGROUND: The global increase in Cesarean section rate is associated with short- and long-term complications, including adhesions with potential serious maternal and fetal consequences. This study investigated the prevalence of adhesions and association between adhesions and postoperative complications in a tertiary referral hospital in Accra, Ghana. METHODS: In this prospective cohort study, 335 women scheduled for cesarean section at Korle-Bu Teaching Hospital in Accra, Ghana were included from June to December 2015. Presence or absence of adhesions was recorded and the severity of the adhesions was scored using a classification system. Associations between presence and severity of adhesions, postoperative complications, and maternal and infant outcomes at discharge and 6 weeks postpartum were assessed using multivariate logistic and linear regression analysis. RESULTS: Of the participating women, 128 (38%) had adhesions and 207 (62%) did not. Prevalence of adhesions increased with history of caesarean section; 2.8% with no CS but may have had an abdominal surgery, 51% with one previous CS, 62% with >1 CS). Adhesions significantly increased operation time (mean 39.2 (±15.1) minutes, absolute adjusted difference with presence of adhesions 9.6 min, 95%CI 6.4-12.8), infant delivery time (mean 5.4 (±4.8) minutes, adjusted difference 2.4 min, 95%CI 1.3-3.4), and blood loss for women with severe adhesions (mean blood loss 418.8 ml (±140.6), adjusted difference 57.6 ml (95%CI 12.1-103.0). No differences for other outcomes were observed. CONCLUSION: With cesarean section rates rising globally, intra-abdominal adhesions occur more frequently. Risks of adhesions and associated complications should be considered in counseling patients for cesarean section. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12978-017-0388-0) contains supplementary material, which is available to authorized users.
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spelling pubmed-56674412017-11-08 Prevalence of adhesions and associated postoperative complications after cesarean section in Ghana: a prospective cohort study Nuamah, Mercy A. Browne, Joyce L. Öry, Alexander V. Damale, Nelson Klipstein-Grobusch, Kerstin Rijken, Marcus J. Reprod Health Research BACKGROUND: The global increase in Cesarean section rate is associated with short- and long-term complications, including adhesions with potential serious maternal and fetal consequences. This study investigated the prevalence of adhesions and association between adhesions and postoperative complications in a tertiary referral hospital in Accra, Ghana. METHODS: In this prospective cohort study, 335 women scheduled for cesarean section at Korle-Bu Teaching Hospital in Accra, Ghana were included from June to December 2015. Presence or absence of adhesions was recorded and the severity of the adhesions was scored using a classification system. Associations between presence and severity of adhesions, postoperative complications, and maternal and infant outcomes at discharge and 6 weeks postpartum were assessed using multivariate logistic and linear regression analysis. RESULTS: Of the participating women, 128 (38%) had adhesions and 207 (62%) did not. Prevalence of adhesions increased with history of caesarean section; 2.8% with no CS but may have had an abdominal surgery, 51% with one previous CS, 62% with >1 CS). Adhesions significantly increased operation time (mean 39.2 (±15.1) minutes, absolute adjusted difference with presence of adhesions 9.6 min, 95%CI 6.4-12.8), infant delivery time (mean 5.4 (±4.8) minutes, adjusted difference 2.4 min, 95%CI 1.3-3.4), and blood loss for women with severe adhesions (mean blood loss 418.8 ml (±140.6), adjusted difference 57.6 ml (95%CI 12.1-103.0). No differences for other outcomes were observed. CONCLUSION: With cesarean section rates rising globally, intra-abdominal adhesions occur more frequently. Risks of adhesions and associated complications should be considered in counseling patients for cesarean section. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12978-017-0388-0) contains supplementary material, which is available to authorized users. BioMed Central 2017-11-02 /pmc/articles/PMC5667441/ /pubmed/29096649 http://dx.doi.org/10.1186/s12978-017-0388-0 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Nuamah, Mercy A.
Browne, Joyce L.
Öry, Alexander V.
Damale, Nelson
Klipstein-Grobusch, Kerstin
Rijken, Marcus J.
Prevalence of adhesions and associated postoperative complications after cesarean section in Ghana: a prospective cohort study
title Prevalence of adhesions and associated postoperative complications after cesarean section in Ghana: a prospective cohort study
title_full Prevalence of adhesions and associated postoperative complications after cesarean section in Ghana: a prospective cohort study
title_fullStr Prevalence of adhesions and associated postoperative complications after cesarean section in Ghana: a prospective cohort study
title_full_unstemmed Prevalence of adhesions and associated postoperative complications after cesarean section in Ghana: a prospective cohort study
title_short Prevalence of adhesions and associated postoperative complications after cesarean section in Ghana: a prospective cohort study
title_sort prevalence of adhesions and associated postoperative complications after cesarean section in ghana: a prospective cohort study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667441/
https://www.ncbi.nlm.nih.gov/pubmed/29096649
http://dx.doi.org/10.1186/s12978-017-0388-0
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