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TLR2 stimulation impairs anti-inflammatory activity of M2-like macrophages, generating a chimeric M1/M2 phenotype

BACKGROUND: Toll-like receptors (TLRs) and macrophages play an important role in rheumatoid arthritis (RA). Currently, it is not clear whether inflammatory M1 or anti-inflammatory M2 predominate among the resident macrophages in the synovium. In the present study, we set out to investigate the impac...

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Detalles Bibliográficos
Autores principales:	Quero, Lilian, Hanser, Edveena, Manigold, Tobias, Tiaden, André N., Kyburz, Diego
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667453/ https://www.ncbi.nlm.nih.gov/pubmed/29096690 http://dx.doi.org/10.1186/s13075-017-1447-1

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