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QNB: differential RNA methylation analysis for count-based small-sample sequencing data with a quad-negative binomial model
BACKGROUND: As a newly emerged research area, RNA epigenetics has drawn increasing attention recently for the participation of RNA methylation and other modifications in a number of crucial biological processes. Thanks to high throughput sequencing techniques, such as, MeRIP-Seq, transcriptome-wide...
Autores principales: | Liu, Lian, Zhang, Shao-Wu, Huang, Yufei, Meng, Jia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667504/ https://www.ncbi.nlm.nih.gov/pubmed/28859631 http://dx.doi.org/10.1186/s12859-017-1808-4 |
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