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Integrating proteomics with electrochemistry for identifying kinase biomarkers
We present an integrated approach for highly sensitive identification and validation of substrate-specific kinases as cancer biomarkers. Our approach combines phosphoproteomics for high throughput cancer-related biomarker discovery from patient tissues and an impedimetric kinase activity biosensor f...
Autores principales: | Amit, Einav, Obena, Rofeamor, Wang, Yi-Ting, Zhuravel, Roman, Reyes, Aaron James F., Elbaz, Shir, Rotem, Dvir, Porath, Danny, Friedler, Assaf, Chen, Yu-Ju, Yitzchaik, Shlomo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667508/ https://www.ncbi.nlm.nih.gov/pubmed/29142712 http://dx.doi.org/10.1039/c5sc00560d |
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