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Galectin-1 and galectin-3 expression in equine mesenchymal stromal cells (MSCs), synovial fibroblasts and chondrocytes, and the effect of inflammation on MSC motility

BACKGROUND: Mesenchymal stromal cells (MSCs) can be used intra-articularly to quell inflammation and promote cartilage healing; however, mechanisms by which MSCs mitigate joint disease remain poorly understood. Galectins, a family of β-galactoside binding proteins, regulate inflammation, adhesion an...

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Detalles Bibliográficos
Autores principales: Reesink, Heidi L., Sutton, Ryan M., Shurer, Carolyn R., Peterson, Ryan P., Tan, Julie S., Su, Jin, Paszek, Matthew J., Nixon, Alan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667510/
https://www.ncbi.nlm.nih.gov/pubmed/29096716
http://dx.doi.org/10.1186/s13287-017-0691-2