Asymptomatic Meningitis and Lung Cavity in a Case of Cryptococcosis

Patient: Male, 52 Final Diagnosis: Cryptococcosis Symptoms: Forehead skin lesions and fever Medication: — Clinical Procedure: — Specialty: Infectious Diseases OBJECTIVE: Unusual clinical course BACKGROUND: Cryptococcus neoformans (C. neoformans) infection is one of the most common opportunistic infections in AIDS patients. C. neoformans usually infects the central nervous system (CNS) and/or lungs with typical clinical manifestation. CASE REPORT: Here, we report the case of a 52-year-old HIV-1-infected man with disseminated cryptococcosis, including sub-acute meningitis, pulmonary, and cutaneous cryptococcosis, but only skin lesion served as the chief complaint. Moreover, the results of cerebrospinal fluid (CSF) tests and lung computed tomography (CT) scan were atypical. CONCLUSIONS: We present the clinical characteristics of this case and discuss the diagnostic procedure, which will likely help clinicians in making a timely definitive diagnosis of this disease.